Senior Python jobs in South Africa
45 open right now — Senior roles, mentioning Python, in South Africa. Read straight from companies’ own boards, and every listing links to the original posting.
Of the 25 newest shown here, 3 state pay and 21 are remote, from 17 employers.

Senior Software Engineer (Javascript)
Boardroom Appointments · Remote (South Africa)
RemoteFull-timeSeniorFull Stack Solution Architect role
SavageOne · Remote (South Africa)
RemoteFull-timeSeniorZAR 40K – ZAR 50K/yr ·
Senior Solution Architect
SavageOne · Remote (South Africa)
RemoteFull-timeSeniorZAR 70K – ZAR 100K/yr ·
Senior Back-End Engineer (South Africa - Remote)
Draslovka · Remote (South Africa)
RemoteFull-timeSenior
Senior Product Manager, Buyability & Selection, Retail Operations and Initiatives
Amazon Commercial Services Pty Ltd · Cape Town, South Africa
Full-timeSenior- Senior Software Engineer - Applied AI and Integrations
Lifted (an Upwork Company) · Remote (South Africa)
RemoteContractSeniorAI and Data Platforms Lead (1 year contract)
African Climate Foundation · Remote (South Africa)
RemoteContractSeniorSenior Product/Marketing Analyst
The Global Talent Co. · Remote (South Africa)
RemoteFull-timeSenior25K/yr ·